Position Overview & Specifications

Job Description General Summary: We are recruiting a highly motivated Research Scientist to work in an innovative drug discovery group who could play a pivotal role in expanding our translational biomarker capabilities. Successful candidates will help us utilise a range of molecular biology techniques and state-of-the-art in vitro modelling to translate biology insights into clinically meaningful assays to characterise potential drug candidates. This work is vitally important for ensuring that we deliver medicines that treat the underlying cause of serious diseases and provide transformative benefit for our patients.
Key Duties and Responsibilities:
  • Implementation of robust and sensitive methods using cutting edge molecular biology techniques and assay platforms to support biomarker discovery and development
  • Independently design and execute insightful pre-clinical research studies using relevant in vitro models and patients’ samples/biofluids
  • Proactive communication and close collaboration with clinical biomarker and imaging teams
  • Effectively distil complex, multi-dimensional data and results into concise concepts and clearly propose strategic and experimental actions
  • Use contemporary and relevant scientific literature and routinely incorporate new insights into research activities

Knowledge and Skills:
  • Track record of accomplishments in solving complex scientific problems with evidence of individual and collaborative contributions
  • Experience in using cell models and primary patient tissues to understand causative disease processes
  • Demonstrates a strong understanding of fundamental pharmacology principles to design and execute insightful experiments to understand compound effects & mechanism of action
  • Laboratory experience of molecular biology techniques including qPCR, ELISA, western blotting, and IHC
  • Excellent verbal and written communication skills to engage effectively with a wide-ranging audience, both orally and in writing
  • Highly motivated and curious individual; happy to work across a broad range of biological subjects and projects

Education and Experience:
  • PhD obtained in a relevant Biological Science (e.g Cellular and Molecular biology, Pharmacology) or MSc with relevant experience in translational research/biomarker discovery
Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Please note that Vertex requires COVID-19 vaccination for all employees working in the U.S. as a condition of employment at Vertex, subject to medical, religious or other accommodations or exemptions required by law. We believe this requirement is vital to keeping everyone at Vertex and in our communities safe. This requirement applies to both existing and new employees who may at any time work on-site at a Vertex facility or visit another location on behalf of Vertex (e.g., conferences, customer visits, etc.), including all remote employees. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com.